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CMAJ
CMAJ - December 14, 1999JAMC - le 14 decembre 1999

Please pass the strychnine: the art of Victorian pharmacy

Table 4: Medicines commonly prescribed in the early 1900s
Class of drugs Drug, reasons drug was prescribed

Bitter tonics/stimulants Quinine sulfate — to stimulate appetite; a "specific" for malaria; for amebic dysentery, reducing fever and hyperthyroidism
Nux vomica (1.25% strychnine) — stimulant for shock; to improve muscle tone, increase appetite, ("tonic" effect), and stimulate weak bladder and as an antidote for narcotic overdose
Cocaine muriate — stimulant; local anaesthetic; used to relieve coryza, vomiting and hiccough
Analgesics Morphine sulfate — to relieve pain; as a hypnotic; for gall stones and kidney colic; general anesthetic with scopolamine/atropine; diarrhea control; cough suppressant; to relieve asthma
Ethyl ether — anticonvulsant; antiasthmatic; anti-anginal but also given internally to lessen gas in the stomach (colic)
Chloroform — anticonvulsant; internally as an antidiarrheal; anticolic; and in liniment for local pain
Cardiotonics Caffeine citrate — heart stimulant
Digitalis (foxglove) — atrial fibrillation/flutter; "weak heart;" shock and cardiovascular collapse
Diuretics/purgatives Calomel (mercury chloride) — laxative; antisyphilitic; antihelminthic
Cascara sagrada — laxative
Miscellaneous Ipecac — small dose, expectorant; larger dose, emetic
Pilocarpine — principally to produce sweating for waste elimination; for edema in nephritis; glaucoma; hair tonic; for eczema, scleroderma, urticaria and dizziness due to labyrinthitis; stimulation of lung secretions
Belladonna (deadly nightshade) — contains atropine and used to treat asthma attacks, gastric ulcer, hiccoughs and biliary colic; cardiac stimulant

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