| Table 2: Rates of first occurrence of stroke, stroke and transient ischemic attack (TIA) combined, and any bleeding episode for the 4 treatment groups |
|
| |
Treatment |
| |
|
| Outcome event |
ASA |
Warfarin |
Blended |
None |
|
|
Stroke |
|
|
|
|
| No. of person-years |
76.5 |
217 |
74.9 |
118.6 |
| No. of patients with event |
4 |
4 |
4 |
7 |
| Hazard (rate per 100 person-years) |
5.2 |
1.8 |
5.3 |
5.9 |
| Rate ratio (and 95% confidence interval)* |
0.88
(0.25–3.05) |
0.31
(0.09–1.00) |
0.90
(0.27–3.03) |
– |
|
Stroke and TIA combined |
| No. of person-years |
76.5 |
216.1 |
70.5 |
118.6 |
| No. of patients with event |
4 |
5 |
7 |
8 |
| Hazard (rate per 100 person-years) |
5.2 |
2.3 |
9.9 |
6.7 |
| Rate ratio (and 95% confidence interval)* |
0.78
(0.24–2.50) |
0.34
(0.12–0.99) |
1.48
(0.53–4.11) |
– |
|
Bleeding |
|
|
|
|
| No. of person-years |
60.9 |
142.5 |
51 |
99.6 |
| No. of patients with event |
15 |
49 |
18 |
19 |
| Hazard (rate per 100 person-years) |
2.5 |
3.4 |
3.5 |
1.9 |
| Rate ratio (and 95% confidence interval)* |
1.32
(0.63–2.75) |
1.79
(1.07–3.00) |
1.84
(0.9–3.45) |
– |
|
| *Reference group = no treatment. |
